Optogenetics
Blue light triggers protein aggregation on command, so pathology forms on a schedule we choose instead of over decades.
human Pluripotent Stem Cell-based Disease modeling and Therapeutics
Genetically engineered human iPSCs, optogenetics, SMASh-tagging and CRISPR-Cas9, aimed at Parkinson's disease, dementia and diabetic neuropathy.

We're at the forefront of developing stem-cell-based strategies for neurological diseases, leveraging cutting-edge technologies including Optogenetics, SMASh-tagging, and CRISPR-Cas9, through collaboration with our students and researchers.
CRISPR-Cas9 유전자 편집, Optogenetics(광유전학), SMASh-tagging과 같은 최신 기술을 이용하여 유전적으로 변형된 인간 만능줄기세포를 제작하고, 이를 분화하여 파킨슨병, 치매, 당뇨성 신경병증 등 다양한 신경 질환을 모델링하고 새로운 치료 전략을 개발합니다.
Blue light triggers protein aggregation on command, so pathology forms on a schedule we choose instead of over decades.
A small-molecule-assisted shutoff tag lets us dial protein levels down with a drug, turning any gene into a tunable one.
Isogenic lines carrying patient mutations, reporters and safety switches, built in-house for every model we study.
* Co-first authors · # Co-corresponding authors

We're recruiting passionate postdoctoral researchers, graduate students and undergraduate researchers. Send a CV and a short note about what you want to work on.
열정적인 박사후연구원, 대학원생, 학부연구생을 모집합니다.